Risk of non-infectious elephantiasis mapped in Cameroon

Both the etiology and demographics of podoconiosis, a non-infectious disease which causes massive swelling of the legs, are poorly understood. To help contribute to the global atlas of podoconiosis knowledge, researchers reporting in PLOS Neglected Tropical Diseases have now described the distribution of podoconiosis in Cameroon.

Podoconiosis, a non-filarial form of elephantiasis which was identified as a neglected tropical disease by the World Health Organization in 2011, arises in barefoot subsistence farmers who are in frequent contact with red volcanic clay soil. Podoconiosis is one of several neglected diseases causing pain, disability and disfigurement that contribute to the world’s poorest and most vulnerable communities remaining in a cycle of poverty and disease. The disease has been reported in more than 32 countries, with an estimated 4 million cases worldwide. However, Ethiopia is the only country where podoconiosis risk has been extensively mapped.

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Specific control methods include the use of footwear, regular foot hygiene and floor coverings. For those with the diseases management of the lymphedema-related morbidity is recommended which includes foot hygiene, foot care, wound care, compression, exercises, elevation of the legs and treatment of acute infections.

In the new work, Kebebe Deribe, Postdoctoral Research Fellow of Brighton and Sussex Medical School, UK, and colleagues, sampled 76 villages from 40 health districts in Cameroon. In each village, all individuals age 15 and older were surveyed and screened for lymphedema–the swelling that is indicative of elephantiasis. In cases of lymphedema, other diagnoses, including the filarial forms of elephantiasis, were excluded using field tests.

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